Investigation of liver tissue and biochemical parameters of adult wistar rats treated with Arctium lappa L.

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Investigation of Liver Tissue and Biochemical Parameters of Adult Wistar Rats treated with Arctium lappa L

This study was carried out to evaluate the effects of Arctium lappa L. (burdock) on the liver of adult male Wistar rats as measured by light microscopy and biochemical parameters. The rats received the extract in water bottles at doses of 10 or 20 g/L daily for 40 days. There were no significant changes in the plasma levels of albumin, aspartate transaminase (AST), alanine transaminase (ALT), g...

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 Background & Objective: Cyclophosphamide is an antineoplastic drug that has many clinical uses in cancer treatment, but it has toxic effects due to creation of free radicals. In this study, the effects of curcumin" as an antioxidant drug” on liver tissue was investigated. Materials & methods: 50 wistar adult male rats were selected randomly and were divided in to five groups including co...

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Safety Assessment of Arctium lappa L. Fruit Extract in Female Wistar Rats: Acute and Repeated Oral Toxicity Studies

Background and objectives: Arctium lappa belonging to the Compositae (Asteraceae) family has been used as a medicinal and nutritional supplement in the world. The fruits, leaves and roots of the plant are well-known for their pharmaceutical effects. Toxicity of the fruit’s extract in female rats was investigated in the present study. Methods: To assess...

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Protective Effect of Spirulina and Phycocyanin on Testicular Tissue and Sperm Parameters in Adult Rats Treated with Hydrogen Peroxide

 Background and purpose: About 50% of infertility in couples is related to male factors and oxidative stress is one of the main causes of infertility in men. Hydrogen peroxide has an adverse effect on male reproductive system due to its free radicals. Spirulina and phycocyanin are known to have antioxidant properties and can modify stressors. Materials and methods: In this experimental study, ...

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Safety of 8-weeks oral administration of Arctium lappa L.

Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material s...

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ژورنال

عنوان ژورنال: Brazilian Archives of Biology and Technology

سال: 2009

ISSN: 1516-8913

DOI: 10.1590/s1516-89132009000200010